Altenative Testing Methods

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We often hear the question- „If it’s not tested on animals, how can we make sure the products are safe to use?"

The truth is animal testing is completely outdated and unnecessary. Modern approaches that are cheaper, faster and can better predict the human reactions are widely available. More than 30 countries around the world, including the European Union now require their use.

 We want to be sure to let you know some alternative ways for brands to avoid testing on animals. In order to be considered an "alternative", a method must meet the "three R's": Replace, Reduce, and Refine. 

We want to be sure to let you know some alternative ways for brands to avoid testing on animals. In order to be considered an "alternative", a method must meet the "three R's": Replace, Reduce, and Refine.

REPLACE a subject to avoid using animals

REDUCE the number of animals used or effected

REFINE a procedure to minimize or get ride of animal pain. 

According to the Humane Society of the U.S., there are more than 50 identified alternatives! (YAY!!) To name a few:

1. Lab-grown epidermis 

We know that sounds creepy, but no worries, it comes from human stem cells. These stem cells in our skin multiply constantly, so doesn't it sound better to use our own skin than pets? We think yes. 

2. In Silico

This is a computer simulation model and becoming more and more popular. It's quick and efficient and tests toxicity of chemicals on a human model. This method is time as well as cost efficient. 

3. Human trials

Wouldn't this method make the most sense, since we are the ones that are going to be using the product? Probably. There are ways to safely do it by micro-dosing and microchip technologies. Using small doses, it can safely be tested if there is any reaction. 

4. Pyrogenicity - using five human cells in this procedure with human whole blood, for detecting pyrogenicity by Gram-negative endotoxins. Pyrogenicity is another word for a vascular lesion or irritation on skin. 
5. Reproductive & Developmental Toxicity - embryonic stem cell test for embryotoxicity, meaning being toxic to an embryo, resulting in abnormal development. 
6.  Biologics & Vaccines - using human tetanus vaccines to test potency; getting rid of target-animal batch safety test. 
7. Ecotoxicity - acute aquatic toxicity, using water, upper threshold concentration step-down approach. This pertains to aquatic ecology and aquatic chemistry, meaning this deals with freshwater, marine water, and sediment environments that marine animals use. 
8. Eye Irritation - using human cornea-like epithelium test method to identify chemicals not requiring classification in test methods that cause damage to the eye or eye irritation. This would be applying a routine use of topical anesthetics. 
9. Genotoxicity - Using in vitro methods, this alternative method is a reverse bacterial mutation test. This is testing the interactions of mammalian cells. 
10. Metabolism - No, not concerning weight this time! This is testing human drug-drug interactions, enzyme induction, using metabolizing systems for in vitro testing of endocrine disruptors. Endoncrine disruptors are chemicals that can interfere with endocrine systems at certain doses. Disruptions can cause cancerous tumors, birth defects, and other developmental disorders. 

So let's work together to spread the word about ending animal testing and push brands to use alternative methods instead that are more efficient, deliver faster results, are more cost effective and our furry friends won't be paying the price.

(Source: Social Compassion In Legislation)

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